Anti-CRSP9抗體,轉(zhuǎn)錄激活蛋白CRSP9抗體科研產(chǎn)品介紹:
In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1). These complexes include the SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes, and including the human proteins Srb7, Med6 (also designated DRIP33) and Med7 (also designated DRIP34) (2,3). SMCC associates with the RNAPII (RNA polymerase II) holoenzyme through Srb7 and, in turn, enhances gene-specific activation or repression induced by DNA-binding transcription factors (4). Med6 and Med7, as well as other components of SMCC, associate with coactivator proteins from the TRAP (thyroid hormone receptor-activating protein) complex and DRIP (for vitamin D receptor interacting protein) complex to facilitate steroid receptor dependent transcriptional activation (4,5). Additionally, SMCC associates with PC4 (positive cofactor 4) to repress basal transcription independent of RNAPII activity (6).

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產(chǎn)品詳情:
產(chǎn)品編號(hào):HRK-11427R
產(chǎn)品規(guī)格: 0.1ml/0.2ml
產(chǎn)品別名:Cofactor required for Sp1 transcriptional activation subunit 9; CRSP complex subunit 9; CRSP33; hMED7; MED7; MED7_HUMAN; Mediator complex subunit 7; Mediator of RNA polymerase II transcription subunit 7; MGC12284; RNA polymerase transcriptional regulation mediator subunit 7 homolog; Transcriptional coactivator CRSP33; Activator recruited cofactor 34 kDa component; Activator-recruited cofactor 34 kDa component; ARC34
產(chǎn)品價(jià)格:詢價(jià)(電詢或客服)
產(chǎn)品用途:科研實(shí)驗(yàn)
貯 存: 貯存于-20℃.
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