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當前位置:華瑞科研網-ELISA試劑盒>>科研抗體>>磷酸化抗體>>Anti-Phospho-BRCA1(Ser1280),磷酸化乳腺癌易感基因1抗體科研

Anti-Phospho-BRCA1(Ser1280),磷酸化乳腺癌易感基因1抗體科研

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更新時間:2015-03-20 09:23:23瀏覽次數:191次

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聯系人:韓經理 (銷售)

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“Anti-Phospho-BRCA1(Ser1280),磷酸化乳腺癌易感基因1抗體科研"我公司擁有*的細胞服務技術,*的儀器設備和專業的ELISA檢測試劑盒、生物索標記、熒光索標記、酶標記等,廣泛用于多種分析研究與技術測定。咨詢,我們將竭誠為你服務!

詳細介紹

Anti-Phospho-BRCA1(Ser1280),磷酸化乳腺癌易感基因1抗體科研產品介紹:

This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximay 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. 


與“Anti-Phospho-BRCA1(Ser1280),磷酸化乳腺癌易感基因1抗體科研"有關的產品:

Anti-CYP450(Cytochrome P450 monooxygenase)  細胞色素P450單氧化酶抗體
Anti-Cyr61/IGFBP10/CCN1(cysteine rich 61)  富半*肝素結合蛋白61抗體
Anti-CYP2E1(cytochrome P450 2E1)  抗細胞色素P450ⅡE1抗體
Anti-Cytochrome C  細胞色素 C抗體
Anti-DRD1 receptor (dopamine D1 receptor)  多巴胺受體-D1抗體
Anti-DRD2 receptor(dopamine D2 receptor)  多巴胺受體-D2抗體
Anti-DRD3 receptor(dopamine D3 receptor)  多巴胺受體-D3抗體
Anti-DAT1(dopamine transporter)  抗多巴胺相關轉錄因子1抗體
Anti-DRD4 receptor(Dopamine D4 Receptor )  多巴胺受體-D4抗體
Anti-DRD5 receptor(dopamine D5 receptor)  多巴胺受體-D5抗體

Anti-Phospho-BRCA1(Ser1280),磷酸化乳腺癌易感基因1抗體科研產品詳情:
產品編號:HRK-12884R
產品規格: 0.1ml/0.2ml
產品別名:BRCA1 (phospho S1280); BRCA1 (phospho Ser1280); p-BRCA1 (phospho S280); BRCA 1; BRCA1; BRCA1/BRCA2 containing complex subunit 1; BRCA1/BRCA2-containing complex, subunit 1; BRCA1_HUMAN; BRCAI; BRAC 1; BRCA 1; BRCC 1; BRCC1; Breast Cancer 1; Breast Cancer 1 Early Onset; Breast cancer type 1 susceptibility protein; Breast and ovarian cancer susceptibility protein 1; Breast Ovarian Cancer Susceptibility; IRIS; Papillary Serous Carcinoma Of The Peritoneum; PSCP; RING finger protein 53; BROVCA1; IRIS; PNCA4; PPP1R53; Protein phosphatase 1 regulatory subunit 53; RNF53; BAP1
產品價格:詢價(電詢或客服)
產品用途:科研實驗
貯 存:   貯存于-20℃.

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